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Shao B, Pennathur S, Pagani I, Oda MN, Witztum JL, Oram JF, Heinecke JW

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BPC-157 complements these mechanisms through its activation of VEGFR2 and eNOS pathways that promote angiogenesis and improve endothelial function, with the peptide's nitric oxide generation supporting vasodilation and reducing thrombotic risk while its growth factor sensitization enhances vascular responses to ischemic conditions